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Induction of PGE2 by estradiol mediates developmental masculinization of sex behavior

✍ Scribed by Amateau, Stuart K; McCarthy, Margaret M

Book ID
109940465
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
653 KB
Volume
7
Category
Article
ISSN
1097-6256

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## Abstract Prostaglandin E2 (PGE2) mediates the organization of male rat sexual behavior and medial preoptic area (MPOA) neuroanatomy during a sensitive perinatal window. PGE2 is up‐regulated in response to estradiol, and initiates a two‐fold increase in dendritic spines densities on neurons. All