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Induction of p53-Independent Apoptosis by Hygromycin B: Suppression by Bcl-2 and Adenovirus E1B 19-kDa Protein

✍ Scribed by Gang Chen; Philip E. Branton; Gordon C. Shore

Book ID
115602185
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
461 KB
Volume
221
Category
Article
ISSN
0014-4827

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## Abstract ## Objective Rheumatoid arthritis (RA) synovial hyperplasia is related in part to a resistance to apoptosis exhibited by fibroblast‐like synoviocytes (FLS). Since hypoxia is a regulator of apoptosis, and since RA synovium is hypoxic, we conducted this study to examine the effects of hy