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Induction of oxidative DNA damage in human foreskin fibroblast Hs68 cells by oxidized β -carotene and lycopene

✍ Scribed by Yeh, Shu-Lan; Hu, Miao-Lin


Book ID
120043696
Publisher
Informa plc
Year
2001
Tongue
English
Weight
796 KB
Volume
35
Category
Article
ISSN
1071-5762

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## Abstract The mechanism of Cr(VI) genotoxicity has still not been elucidated. We used Fpg‐modified comet assay to assess direct‐oxidative DNA damage on human lung (A549) and bronchial (BEAS‐2B) cells exposed to 0.1, 0.5, 1.0 and 10 μm sodium chromate for 0.5, 1 and 4 h. Moreover we evaluated apop