Induction of ornithine decarboxylase and s-adenosylmethionine decarboxylase by sulfobromophthalein in rats
β Scribed by Takiko Oguro; Satoshi Numazawa; Takemi Yoshida; Yukio Kuroiwa
- Book ID
- 118343569
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 511 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0024-3205
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Oligodeoxynucleotides 18 nucleotides in length having sequences complementary to regions spanning the initiation codon regions of ornithine decarboxylase or S-adenosylmethionine decarboxylase mRNAs were tested for their ability to inhibit translation of these mRNAs. In reticulocyte lysates, a strong
In the present study we have examined the regulation of the polyamine biosynthetic pathway in a cell line deficient in ornithine decarboxylase (ODC) activity. These cells were unable to grow unless polyamines were provided in their growth medium. Seeding the cells in the absence of polyamines rapidl