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Induction of oral tolerance enables growth of hepatoma cell line in mice

✍ Scribed by I. Gotsman; R. Alper; E. Rabbani; D. Engelhardt; Y. Ilan


Book ID
119525800
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
91 KB
Volume
32
Category
Article
ISSN
0168-8278

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## Abstract Adoptive transfer of immunity against hepatitis B surface antigen (HBsAg) was previously shown to facilitate suppression of experimental human hepatocellular carcinoma (HCC) expressing HBsAg in athymic mice. We have shown that oral tolerance induces antigen‐specific immune suppression o

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The clone C2 derived from a rat hepatoma cell line was used to investigate the mechanism of the induction of gamma-glutamyltransferase by ethanol. gamma-glutamyltransferase activity was detected in the C2 cell (1.4 mU per mg protein), and its kinetic properties were similar to normal rat liver gamma