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Induction of nuclear factor-κB responses by the S100A9 protein is Toll-like receptor-4-dependent

✍ Scribed by Matteo Riva; Eva Källberg; Per Björk; Dora Hancz; Thomas Vogl; Johannes Roth; Fredrik Ivars; Tomas Leanderson


Book ID
117947199
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
459 KB
Volume
137
Category
Article
ISSN
0019-2805

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Acute exposure to lipopolysaccharide (LPS) can cause hypoglycemia and insulin resistance; the underlying mechanisms, however, are unclear. We set out to determine whether insulin resistance is linked to hypoglycemia through Toll-like receptor-4 (TLR4), myeloid differentiation factor 88 (MyD88), and