𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Induction of neurite outgrowth in the IMR-32 human neuroblastoma cell line by nerve growth factor

✍ Scribed by C. P. Reynolds; Dr. J. R. Perez-Polo

Publisher
John Wiley and Sons
Year
1981
Tongue
English
Weight
1006 KB
Volume
6
Category
Article
ISSN
0360-4012

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The nerve growth factor protein (NGF) stimulates neurite outgrowth from embryonic sensory ganglia and sympathetic ganglia at all stages of development. In addition, NGF is required for the maintenance of the differentiated state in adult sympathetic ganglia. A clonal cell line, IMR‐32, derived from a human neuroblastoma was found to contain a population of cells that respond to NGF by exhibiting morphological differentiation. The effect of NGF on these cells is compared with that of other agents known to induce differentiation of IMR‐32, including glioma‐conditioned media.

πŸ“œ SIMILAR VOLUMES

Human synapsin I mediates the function o
Human synapsin I mediates the function of nuclear respiratory factor 1 in neurite outgrowth in neuroblastoma IMR-32 cells
✍ Jen-Ling Wang; Wen-Teng Chang; Chih-Wei Tong; Kimitoshi Kohno; A-Min Huang πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 412 KB

## Abstract Nuclear respiratory factor (NRF)‐1 is a transcription factor with a novel function in neurite outgrowth. Synapsin I protein is a well‐known phosphoprotein in neuronal terminals and has been implicated in neuronal differentiation. Human __synapsin I__ gene promoter has a putative NRF‐1 r

Heterogeneity of GABAA receptor-mediated
Heterogeneity of GABAA receptor-mediated responses in the human IMR-32 neuroblastoma cell line
✍ Douglas W. Sapp; Hermes H. Yeh πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 149 KB

The gamma-aminobutyric acid (GABA) response profiles of IMR-32 human neuroblastoma cells were examined using whole-cell patch clamp and RT-PCR techniques. GABA activated a concentration-dependent and bicuculline-sensitive current, and RT-PCR revealed the expression of multiple GABA(A) receptor subun

Expression of p75NTR in a human prostate
Expression of p75NTR in a human prostate epithelial tumor cell line reduces nerve growth factor–induced cell growth by activation of programmed cell death
✍ Beth Pflug; Daniel Djakiew πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 262 KB πŸ‘ 2 views

Epithelial expression of the 75-kDa low-affinity neurotrophin receptor (p75 NTR ) is inversely associated with the malignant progression of the human prostate. To elucidate the function of p75 NTR in the prostate, the human prostate epithelial tumor cell line TSU-pr1, which does not express p75 NTR

Low-density lipoprotein receptor-related
Low-density lipoprotein receptor-related protein mediates in PC12 cell cultures the inhibition of nerve growth factor-promoted neurite outgrowth by pregnancy zone protein and Ξ±2-macroglobulin
✍ Gustavo A. Chiabrando; MarΓ­a C. SΓ‘nchez; Erin L. Skornicka; Peter H. Koo πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 275 KB πŸ‘ 1 views

Human pregnancy zone protein (PZP) is a major pregnancy-associated plasma protein closely related to human alpha(2)-macroglobulin (alpha(2)M). It has been demonstrated that monoamine-activated forms of human and rat alpha(2)M and rat alpha(1)M can bind to TrkA and, respectively, inhibit and stimulat

Inhibition of growth and induction of en
Inhibition of growth and induction of enzyme activities in a clonal human hepatoma cell line (Li-7A): Comparison of the effects of epidermal growth factor and an anti-epidermal growth factor receptor antibody
✍ Aileen F. Knowles πŸ“‚ Article πŸ“… 1988 πŸ› John Wiley and Sons 🌐 English βš– 780 KB

A cloned human hepatoma cell line (Li-7A), possessing epidermal growth factor (EGF) receptors numbering in the range of 10-20 pmol/106 cells, was inhibited in its growth by EGF as well as an antagonist monoclonal antibody (MoAb) to the EGF receptor. The mode of action of the two ligands of EGF recep