Induction of natural killer-like cytotoxicity in cultured human thymocytes
✍ Scribed by María Luisa Toribio; Manuel O. De Landázuri; Miguel López-Botet
- Publisher
- John Wiley and Sons
- Year
- 1983
- Tongue
- English
- Weight
- 637 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0014-2980
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✦ Synopsis
Induction of natural killer-like cytotoxicity in cultured human thymocytes
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## Abstract The results of natural killer cell (NK) studies on 539 normal healthy donors tested from once to 213 times over a seven‐year time span have been presented. NK activity did not vary with donor blood group, Rh type or (in a small sample) HLA type. There was a slight but significant increa
The NKp46 molecule has been proposed to play the role of triggering receptor in the natural cytotoxicity mediated by human NK cells. In this study we have identified the gene encoding the murine NKp46 homologue that we termed MAR-1. The MAR-1 gene is localized on chromosome 7 that is synthenic to th