Induction of Multiple Independent T-Cell Lymphomas in Rats Inoculated with Moloney Murine Leukemia Virus
β Scribed by Alfonso Bellacosa, Pedro A. Lazo, Susan E. Bear, Susan Shinton and Philip N. Tsichlis
- Book ID
- 123636797
- Publisher
- National Academy of Sciences
- Year
- 1989
- Tongue
- English
- Weight
- 969 KB
- Volume
- 86
- Category
- Article
- ISSN
- 0027-8424
- DOI
- 10.2307/33667
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## Abstract Foci of transformed cells, produced by MSV(124), appeared to result only from the primary infection, since this virus stock yielded a virusβnonproducing infection. On the other hand, the majority of foci scored in MSV/MLVβinfected cultures, were generated by multiple secondary infection
## Abstract The genetic determinant responsible for virulence in Moloney murine leukemia virus (MoMuLV) induced Tβcell lymphomagenesis has recently been mapped [J Virol 63:471β480, 1989] by homologous genomic fragment exchange between MoMuLV and MoMuLVβTB to the Clal/Xbal at the 3' end of the genom