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Induction of mPer1 expression by GnRH in pituitary gonadotrope cells involves EGR-1

✍ Scribed by H.E. Sikes Resuehr; D. Resuehr; J. Olcese

Book ID
116734607
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
450 KB
Volume
311
Category
Article
ISSN
0303-7207

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## Abstract Glucagon‐like peptide‐1 (GLP‐1) induces several immediate early response genes such as c‐fos, c‐jun, and early growth response‐1 (Egr‐1), which are involved in cell proliferation and differentiation. We recently reported that exendin‐4 (EX‐4), a potent GLP‐1 agonist, upregulated __Egr‐1