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Induction of Mouse Thymocyte Apoptosis by Inhibitors of Tyrosine Kinases Is Associated with Dephosphorylation of Nuclear Proteins

โœ Scribed by Yutaro Azuma; Yoshiaki Onishi; Yutaka Sato; Harutoshi Kizaki


Book ID
112238811
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
318 KB
Volume
152
Category
Article
ISSN
0008-8749

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## Abstract ZD6474 is a vascular endothelial growth factor receptor (VEGFR) and epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor. The present study was undertaken to investigate the direct antiproliferative effect of ZD6474 on human nasopharyngeal carcinoma (NPC) __in vitro__ and t