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Induction of mitogen-activated protein kinase signal transduction pathway during gastric ulcer healing in rats

✍ Scribed by Rama Pai; Masayuki Ohta; Rabiha M. Itani; I.James Sarfeh; Andrzej S. Tarnawski


Book ID
118520534
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
186 KB
Volume
114
Category
Article
ISSN
0016-5085

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✍ Michele A. Brogley; Marcella Cruz; Herman S. Cheung πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 237 KB πŸ‘ 1 views

Synovial fluid basic calcium phosphate (BCP) crystals are markers of severe joint degeneration in osteoarthritis. These crystals are mitogenic and induce protooncogene expression and matrix metalloproteinase (MMP) synthesis and secretion in human fibroblasts, effects that are specifically blocked by