Induction of micronuclei in mouse erythrocytes by Cr6+
β Scribed by Yu. V. Pashin; S. N. Toroptsev
- Publisher
- Springer US
- Year
- 1983
- Tongue
- English
- Weight
- 511 KB
- Volume
- 95
- Category
- Article
- ISSN
- 0007-4888
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Genotoxic effects of five widely used aromatic industrial solvents, ethylbenzene, methylbenzene (toluene), o-, m-, and p-dimethylbenzene (xylene), on bone marrow cells of male NMRI mice were studied using micronucleus test. Each compound was given to animals by IP administration of two similar doses
## Abstract This study investigates the kinetics of bone marrow micronucleated polychromatic erythrocytes and some mechanistic aspects of micronuclei induction using mathematical models. Female mice were administered a single intraperitoneal injection of the purine antagonist 6βmercaptopurine at 50