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Induction of metallothionein in the livers of female Sprague-Dawley rats treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin

✍ Scribed by Noriko Nishimura; Yuichi Miyabara; Junko S. Suzuki; Mikio Sato; Yasunobu Aoki; Masahiko Satoh; Junzo Yonemoto; Chiharu Tohyama

Book ID: 117173075
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 458 KB
Volume: 69
Category: Article
ISSN: 0024-3205
DOI: 10.1016/s0024-3205(01)01212-7

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## Abstract The cancer bioassay for 2,3,7,8‐tetrachlorodibenzo‐__p__‐dioxin (TCDD) conducted by the Dow Chemical company in the mid 70s has been used extensively for conducting quantitative cancer risk assessments for human exposure to TCDD. More recently the National Toxicology Program (NTP) condu