Induction of meiosis in yeast
โ Scribed by A. F. Croes
- Publisher
- Springer-Verlag
- Year
- 1967
- Tongue
- English
- Weight
- 575 KB
- Volume
- 76
- Category
- Article
- ISSN
- 0032-0935
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Premeiotic association of homologous chromosomes in the yeast, Saccharomyces cerevisiae has been shown, by means of fluorescent in situ hybridization Time course and mutant studies show that the premeiotic associations are disrupted upon entry into meiosis, to be reestablished shortly before synapsi
Hydroxyurea (HU) inhibits the premeiotic DNA replication and the meiotic events that followed, namely readiness, recombination commitment, haploidisation, sporulation commitment and ascus formation. Short incubations with HU (2-4 hrs) during the premeiotic replication (i.e. starting between 3 and 6.