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Induction of intestinal cytochrome P450 (CYP3A) by rifampicin in beagle dogs

✍ Scribed by Yoshimasa Kyokawa; Yasuhiro Nishibe; Mitsuko Wakabayashi; Toshio Harauchi; Toshiyuki Maruyama; Takahiko Baba; Kouji Ohno

No coin nor oath required. For personal study only.

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Cytochrome P450 Induction by Rifampicin

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Figure 1. Product distributions in the oxidation of alkylbenzenes by wildtype CYP102A1 (WT) and variant KT5 (F87A7A330P/E377A/D425N).