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Induction of interleukin 2 receptor expression with muramyl dipeptide on murine B lymphocytes

✍ Scribed by T. Saito-Taki; T. Diamantstein; M. Nakano

Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
91 KB
Volume
10
Category
Article
ISSN
0192-0561

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## Abstract DAB~486~IL‐2 is a genetically engineered fusion protein consisting of a portion of diphtheria toxin fused to human IL‐2. It is specifically cytotoxic for tumor cells which bear high‐affinity IL‐2 receptors (IL‐2R). DAB~389~IL‐2 is a similarly constructed hybrid protein which is smaller