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Induction of human γ-globin gene expression by histone deacetylase inhibitors

✍ Scribed by Hua Cao

Book ID: 116304218
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 55 KB
Volume: 38
Category: Article
ISSN: 1079-9796
DOI: 10.1016/j.bcmd.2006.10.027

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## Abstract Valproic acid (VPA) has been used as an anticonvulsant agent for the treatment of epilepsy, as well as a mood stabilizer for the treatment of bipolar disorder, for several decades. The mechanism of action for these effects remains to be elucidated and is most likely multifactorial. Rece