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Induction of homologous recombination following in utero exposure to DNA-damaging agents

✍ Scribed by Karia, Bijal; Martinez, Jo Ann; Bishop, Alexander J.R.


Book ID
121958493
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
669 KB
Volume
12
Category
Article
ISSN
1568-7864

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## Abstract Fetal mice are more sensitive to chemical carcinogens than are adults. We previously demonstrated that resistant offspring of a DBA/2 × (C57BL/6 × DBA2) backcross exhibited a high incidence of lung tumors 12–13 mo after transplacental exposure to 3‐methylcholanthrene (MC). We compared t