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Induction of HL-60 leukemia cell differentiation by tetrahydrofolate inhibitors of de novo purine nucleotide biosynthesis

✍ Scribed by John A. Sokoloski; G. Peter Beardsley; Alan C. Sartorelli

Book ID
104886604
Publisher
Springer
Year
1991
Tongue
English
Weight
651 KB
Volume
28
Category
Article
ISSN
0344-5704

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## Abstract Various compounds active in promoting in vitro differentiation of certain murine leukemia cell lines (Friend erythroleukemia cells and mouse myeloid leukemia cells) were tested for their capacity to induce differentiation of HL‐60 cells, a human promyelocytic leukemia cell line capable