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Induction of hepatic heme oxygenase-1 by diclofenac in rodents: role of oxidative stress and cytochrome P-450 activity

✍ Scribed by Lavinia Cantoni; Rea Valaperta; Xavier Ponsoda; José V Castell; Davide Barelli; Milena Rizzardini; Alessandra Mangolini; Lisa Hauri; Pia Villa

Book ID
118565970
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
397 KB
Volume
38
Category
Article
ISSN
0168-8278

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Induction of heme oxygenase-1 expression
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## Abstract Heme oxygenase‐1 (HO‐1) is known as a stress‐inducible protein and functions as an antioxidant enzyme. It has been shown that HO‐1 is induced rapidly by a variety of chemical and physical stimuli. However, little is known about the induction of cellular signaling events after cell expos