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Induction of heme oxygenase-1 is involved in anti-proliferative effects of paclitaxel on rat vascular smooth muscle cells

✍ Scribed by Byung-Min Choi; Young-Myeong Kim; Young-Ran Jeong; Hyun-Ock Pae; Choong-Eui Song; Jeong-Euy Park; Young-Keun Ahn; Hun-Taeg Chung

Book ID: 116288848
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 406 KB
Volume: 321
Category: Article
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2004.06.120

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## Abstract Extracellular acidosis (EA) regulates Heme Oxygenase‐1 (HO‐1) expression in vascular smooth muscle cells via transcriptional and posttranscriptional mechanisms but the signaling pathways involved are not known. We examined the role of Mitogen‐Activated Protein Kinase (MAPK) pathways in

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