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Induction of Heat Shock Factor-1 by Helicobacter pylori Blocks NF-κB Activation and the Innate Immune Response of Gastric Epithelial Cells

✍ Scribed by Alain P. Gobert; Mohammad Asim; Rupesh Chaturvedi; Keith T. Wilson


Book ID
119432199
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
137 KB
Volume
140
Category
Article
ISSN
0016-5085

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## Abstract Recent studies suggest that sodium arsenite downregulates NF‐κB activity by inhibiting phosphorylation and subsequent degradation of IκBα. Many effects of sodium arsenite are secondary to induction of heat shock proteins. The role of the heat shock response in arsenite‐induced inhibitio