Induction of glutamine synthetase by 8-bromo cyclic AMP in primary cultures of rat brain astrocytes
โ Scribed by Stephen R. Max; Mary E. Landry; H. Ronald Zielke
- Publisher
- Springer
- Year
- 1990
- Tongue
- English
- Weight
- 420 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0364-3190
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๐ SIMILAR VOLUMES
The regulation of intracellular cyclic AMP (CAMP) formation by adenosine (Ado) and its analogues has been examined in primary cultures of rat-brain astrocytes and neurons. In the presence of the phosphodiesterase inhibitor, Ro 20-1724, basal levels of cAMP ranged from 40-120 pmoVmg protein in both c
Increases in the mRNA levels of two neuroglial markers, glutamine synthetase (EC 6.3.1.2; GS) and glycerolphosphate dehydrogenase (EC 1.1.1.8; GPDH), were observed in hydrocortisone-treated cultures of astrocytes and oligodendrocytes, respectively, and in C6 cells by Northern blot analysis and in si