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Induction of Fas-mediated extrinsic apoptosis, p21WAF1-related G2/M cell cycle arrest and ROS generation by costunolide in estrogen receptor-negative breast cancer cells, MDA-MB-231

โœ Scribed by Youn Kyung Choi; Hye Sook Seo; Han Seok Choi; Hyeong Sim Choi; Soon Re Kim; Yong Cheol Shin; Seong-Gyu Ko

Publisher
Springer
Year
2011
Tongue
English
Weight
579 KB
Volume
363
Category
Article
ISSN
0300-8177

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Genistein inhibits proliferation similar
Genistein inhibits proliferation similarly in estrogen receptor-positive and negative human breast carcinoma cell lines characterized by P21WAF1/CIP1 induction, G2/M arrest, and apoptosis
โœ Zhi-Ming Shao; Mary L. Alpaugh; Joseph A. Fontana; Sanford H. Barsky ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 222 KB

Genistein has been proposed to be responsible for lowering the rate of breast cancer in Asian women but the mechanism for this chemopreventive effect in vivo is unknown. In this study, we present in vitro evidence that genistein inhibits cell proliferation similarly in ER-positive and ER-negative hu