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Induction of Extrahepatic Biliary Carcinoma by N-Nitrosobis(2-oxopropyl)amine in Hamsters Given Cholecystoduodenostomy with Dissection of the Common Duct

✍ Scribed by Tajima, Yoshitsugu ;Eto, Toshifumi ;Tsunoda, Tsukasa ;Tomioka, Tsutomu ;Inoue, Keiji ;Fukahori, Tomohiro ;Kanematsu, Takashi

Book ID
108580943
Publisher
Wiley (Blackwell Publishing)
Year
1994
Tongue
English
Weight
737 KB
Volume
85
Category
Article
ISSN
0910-5050

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Reduced expression of the Rassf1a gene a
Reduced expression of the Rassf1a gene and its aberrant DNA methylation in pancreatic duct adenocarcinomas induced by N-nitrosobis(2-oxopropyl)amine in hamsters
✍ Kyoko Shimizu; Yumi Itsuzaki; Hiromasa Fujii; Kanya Honoki; Toshifumi Tsujiuchi 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 243 KB

## Abstract Alterations of the __Rassf1a__ gene were investigated in pancreatic duct adenocarcinomas (PDAs) induced by N‐nitrosobis(2‐oxopropyl)amine (BOP) in hamsters. Female Syrian golden hamsters received 70 mg/kg BOP, followed by repeated exposures to an augmentation pressure regimen consisting