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Induction of DNA damage signaling genes in benzidine-treated HepG2 cells

✍ Scribed by Ssu Ching Chen; You-Cheng Hseu; Jia-Chuen Sung; Chin-Hui Chen; Lei-Chin Chen; King-Tom Chung

Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
632 KB
Volume
52
Category
Article
ISSN
0893-6692

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The aim of this study was to investigate the protective effect of isothiocyanates towards N-nitrosamine-induced DNA damage in the single-cell gel electrophoresis (SCGE)/HepG2 assay. None of the isothiocyanates (ITCs) concentrations tested in the presence or absence of formamidopyrimidine-DNA glycosy