## Abstract Coxsackievirus B3 (CVB3) causes acute and chronic myocarditis, which is accompanied by an intense mononuclear leukocyte infiltration. Because myocardial tissue damage may either result from viral infections or from a dysregulated immune response, the susceptibility of human monocytes an
Induction of cytopathic effect and cytokines in coxsackievirus B3-infected murine astrocytes
✍ Scribed by Jun Zeng, Gefei Wang, Weizhong Li, Dangui Zhang, Xiaoxuan Chen…
- Book ID
- 120693284
- Publisher
- BioMed Central
- Year
- 2013
- Tongue
- English
- Weight
- 742 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1743-422X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract The effect of NO‐metoprolol, that is, 3‐nitrooxypivaloyl metoprolol‐amide, a novel NO‐releasing derivative of the β1‐blocking drug metoprolol was investigated in A.CA/SnJ mice infected with coxsackievirus B3 (CVB3) and compared to metoprolol and placebo. Daily treatment of mice with the
In murine acute viral myocarditis, natural killer (NK) cells infiltrate the heart first, followed by activated T-cells, which play an important role in the pathogenesis of the myocardial damage. Because of their multipotential effects, cytokines are thought to play a role in the induction and develo