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Induction of cytochrome P-450 isozymes during long-term nifedipine administration

✍ Scribed by L. F. Gulyaeva; A. Yu. Grishanova; V. M. Mishin; M. Koleva; Ts. Stoichev; V. V. Lyakhovich

Publisher
Springer US
Year
1990
Tongue
English
Weight
219 KB
Volume
109
Category
Article
ISSN
0007-4888

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✍ Lewandowski, Margaret ;Chui, Y. C. ;Levi, Patricia E. ;Hodgson, Ernest πŸ“‚ Article πŸ“… 1990 πŸ› John Wiley and Sons 🌐 English βš– 900 KB

Eight methylenedioxyphenyl (MDP) compounds were examined for their ability to induce cytochrome P450 (P450) in mouse liver. Induction by safrole, isosafrole, and dihydrosafrole was studied in both C57BLl6N (Ah-responsive) and DBA/2N (Ahnonresponsive) male mice after IP administration of 200 mglkglda