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Induction of cytochrome P-450-dependent sulfonylurea metabolism in Streptomyces griseolus

โœ Scribed by James A. Romesser; Daniel P. O'Keefe

Book ID
115759695
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
530 KB
Volume
140
Category
Article
ISSN
0006-291X

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Metabolism of sulfonylurea herbicides by Streptomyces griseolus ATCC 11796 is carried out via two cytochromes P-450, P-450SU1 and P-450SU2. Mutants of S. griseolus, selected by their reduced ability to metabolize a fluorescent sulfonylurea, do not synthesize cytochrome P-450SU1 when grown in the pre