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Induction of CYP1A1 Gene Expression in Mouse Hepatoma Cells by Benzo(e)Pyrene, a Ligand of the 4S Polycyclic Hydrocarbon-Binding Protein

✍ Scribed by K. Sterling; A. Raha; E. Bresnick


Book ID
112265743
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
632 KB
Volume
128
Category
Article
ISSN
0041-008X

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## Abstract In the rat, expression of the __CYP1A1__ gene is closely associated with arylhydrocarbon hydroxylase (AHH) enzyme activity. AHH is an inducible enzyme activity known to play an important role in the bioactivation of polycyclic aromatic hydrocarbons (PAHs) to mutagenic and carcinogenic m