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Induction of cyclo-oxygenase-2 by acute liver allograft rejection and cytomegalovirus infection in the rat

✍ Scribed by Martelius, Timi; Wolff, Henrik; Bruggeman, Cathrien; Höckerstedt, Krister; Lautenschlager, Irmeli


Book ID
113019973
Publisher
Springer
Year
2002
Tongue
English
Weight
249 KB
Volume
15
Category
Article
ISSN
0934-0874

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In vivo, indomethacin blockade of bone formation has been used to illustrate the role of prostaglandins. Indomethacin blocks the constitutive (COX-1) and inducible (COX-2) forms of cyclo-oxygenase, and is therefore nonspecific in its action. To test the hypothesis that COX-2 mediates the bone format