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Induction of crown-gall: Partial homology between tumor-cell DNA, bacterial DNA and the G+C-rich DNA of stressed normal cells

✍ Scribed by Francis Quétier; Thierry Huguet; Etienne Guillé


Book ID
118851255
Publisher
Elsevier Science
Year
1969
Tongue
English
Weight
394 KB
Volume
34
Category
Article
ISSN
0006-291X

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## Abstract Wortmannin (WM) is a potent inhibitor of the catalytic sub‐unit of DNA‐PK, which is involved in one pathway of DNA double‐strand break (DSB) rejoining, and of ATM, which functions upstream in the p53 signaling pathway. WM is known to be an efficient radiosensitizer in a variety of mamma