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Induction of Circular Episomes during Rescue and Replication of Adeno-Associated Virus in Experimental Models of Virus Latency

✍ Scribed by Sergei A. Musatov; Tara A. Scully; Lorita Dudus; Krishna J. Fisher

Book ID
112273164
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
827 KB
Volume
275
Category
Article
ISSN
0042-6822

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## Abstract ## Background Tumor necrosis factor‐related apoptosis‐inducing ligand (TRAIL) induces cell death in various tumor cells, but relatively spares normal cells. Recombinant adeno‐associated virus (rAAV) vectors have a number of advantages including __in vivo__ long‐term gene expression. He