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Induction of chromosomal aberrations in peripheral lymphocytes of human blood in vitro, and of SCEs in bone-marrow cells of mice in vivo by ethanol and its metabolite acetaldehyde

✍ Scribed by G. Obe; A.T. Natarajan; M. Meyers; A. Den Hertog


Book ID
119092038
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
203 KB
Volume
68
Category
Article
ISSN
0165-1218

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Bone-marrow chromosomes were examined from 38 mentally and physically retarded and two psychiatric patients who were being treated with a variety of neuropharmacologic drugs. Twenty of these patients used clozapine (Leponex). The clastogenic effects of clozapine in vitro were studied in the lymphocy