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Induction of chemokines, MCP-1, and KC in the mutant huntingtin expressing neuronal cells because of proteasomal dysfunction

โœ Scribed by Swetha K. Godavarthi; Doronala Narender; Amit Mishra; Anand Goswami; Sudheendra N. R. Rao; Nobuyuki Nukina; Nihar Ranjan Jana


Book ID
111181238
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
458 KB
Volume
108
Category
Article
ISSN
0022-3042

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## Abstract Increasing evidence suggests that the chemokine interleukin (IL)โ€8/CXCL8 plays important roles in CNS development, neuronal survival, modulation of excitability, and neuroimmune response. Recently, we have shown that CXCL8 can acutely modulate ion channel activity in septal neurons expr