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Induction of CD40 Expression and Enhancement of Monoclonal Antibody Production on Murine B Cell Hybridomas by Cross-Linking of IgG Receptors

✍ Scribed by Alicia Martín-López; Francisco García-Camacho; El Hassan Belarbi; Sergio Martínez-Escobar; Antonio Contreras-Gómez; Emilio Molina-Grima


Book ID
109387532
Publisher
American Institute of Chemical Engineers
Year
2007
Tongue
English
Weight
165 KB
Volume
23
Category
Article
ISSN
8756-7938

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Induction by anti-CD40 antibody or solub
✍ Anne Durandy; Claudine Schiff; Jean Yves Bonnefoy; Monique Forveille; Françoise 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 551 KB

## Abstract We studied the ability of B lymphocytes from patients with X‐linked hyper IgM syndrome (HIGM1) to be activated via the CD40 membrane receptor. HIGM1 is caused by a CD40 ligand gene mutation, leading to defective expression on the membrane of activated T lymphocytes. We found that trigge