Induction of c-Met Proto-Oncogene by Epstein-Barr Virus Latent Membrane Protein-1 and the Correlation with Cervical Lymph Node Metastasis of Nasopharyngeal Carcinoma

Prevalence of mutations and 30-bp deleti

Prevalence of mutations and 30-bp deletion in the C-terminal region of Epstein-Barr virus latent membrane protein-1 oncogene in reactive lymphoid tissue and non-nasopharyngeal EBV-associated carcinomas in Hong Kong Chinese

✍ Suet Y. Leung; Siu T. Yuen; Lap P. Chung; Annie S.Y. Chan; Maria P. Wong 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 French ⚖ 70 KB 👁 2 views

A specific variant of Epstein-Barr virus (EBV) with a 30-bp deletion in the C-terminal region of the LMP1 gene has been found in some EBV-associated malignancies. To better understand the tumorigenic role of this LMP1 variant, we used PCR and sequencing to examine the LMP1 gene in 38 EBVassociated c