Induction of bud formation of embryonic mouse tracheal epithelium by fibroblast growth factor plus transferrin in mesenchyme-free culture

BMP4 modulates fibroblast growth factor–

BMP4 modulates fibroblast growth factor–mediated induction of proximal and distal lung differentiation in mouse embryonic tracheal epithelium in mesenchyme-free culture

✍ Brian A. Hyatt; Xiaofei Shangguan; John M. Shannon 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 820 KB

Lung morphogenesis and differentiation require interaction between the epithelium and mesenchyme, which is mediated by diffusible molecules such as fibroblast growth factors (FGFs), bone morphogenetic protein 4 (BMP4), and Shh. We have used mesenchyme-free culture to study the effects of these molec