Induction of Bone Formation Using a Recombinant Adenoviral Vector Carrying the Human BMP-2 Gene in a Rabbit Spinal Fusion Model

ACL reconstruction using bone-tendon-bon

ACL reconstruction using bone-tendon-bone graft engineered from the semitendinosus tendon by injection of recombinant BMP-2 in a rabbit model

✍ Yusuke Hashimoto; Yoshifumi Naka; Kenji Fukunaga; Hiroaki Nakamura; Kunio Takaok 📂 Article 📅 2011 🏛 Elsevier Science 🌐 English ⚖ 435 KB

## Abstract We attempted to generate a bone‐tendon‐bone structure by injecting human‐type recombinant human bone morphogenetic protein‐2 (rhBMP‐2) into the semitendinosus tendon, and an anterior cruciate ligament (ACL) defect was reconstructed by grafting the engineered bone‐tendon‐bone graft. Two