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Induction of autophagy and inhibition of tumorigenesis by beclin 1

✍ Scribed by Levine, Beth; Liang, Xiao Huan; Jackson, Saadiya; Seaman, Matthew; Brown, Kristy; Kempkes, Bettina; Hibshoosh, Hanina

Book ID
109817988
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
351 KB
Volume
402
Category
Article
ISSN
0028-0836

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## Abstract Autophagy, a process of self‐digestion of cellular constituents, regulates the balance between protein synthesis and protein degradation. Beclin 1 represents an important component of the autophagic machinery. It interacts with proteins that positively regulate autophagy, such as Vps34,