Induction of apoptosis-resistant and TGF-β-insensitive murine CD8+ cytotoxic T lymphocytes specific for HIV-1 gp160

Generation of Melan-A/MART-1-specific CD

Generation of Melan-A/MART-1-specific CD8+ cytotoxic T lymphocytes from human naive precursors: Helper effect requirement for efficient primary cytotoxic T lymphocyte induction in vitro

✍ Marina Ostankovitch; Frédérique-Anne Le Gal; Francine Connan; Dorine Chassin; Je 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 French ⚖ 162 KB 👁 2 views

This study investigates the generation of primary melanoma cell-specific cytotoxic T lymphocytes (CTLs) in vitro. Induction of peptide-specific CTLs from unfractionated naive peripheral blood mononuclear cells from HLA-A2 healthy donors was assessed using 2 recently described 9-mer epitopes from the