Induction of apoptosis in HT-29 human colon adenocarcinoma cells by 13-cis-retinoic acid and vitamin E succinate
β Scribed by Byron K. Murray; Brita Brown; Philip M. Scherer; David P. Tomer; Kaedi R. Garvin; Bronwyn G. Hughes; Kim L. O'Neill
- Book ID
- 116801143
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 305 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0271-5317
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The purpose of this study was to document induction of apoptosis by vitamin E succinate (VES; RRR-Ξ±-tocopheryl succinate) in human breast cancer cells in culture and to characterize potential c-jun involvement. VES at 18.8 Β΅M (10 Β΅g/mL) induced DNA synthesis arrest, reduced total cell numbers, and i