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Induction of apoptosis in HL-60 leukemia and B16 melanoma cells by the acronycine derivative S23906-1

✍ Scribed by Jérôme Kluza; Amélie Lansiaux; Nicole Wattez; Marie-Paule Hildebrand; Stéphane Léonce; Alain Pierré; John A. Hickman; Christian Bailly

Book ID
113993023
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
819 KB
Volume
63
Category
Article
ISSN
0006-2952

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✍ Anna M. Dipietrantonio; Tze-chen Hsieh; Susan C. Olson; Joseph M. Wu 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 French ⚖ 200 KB 👁 2 views

We previously reported that all-trans retinoic acid (RA) and fenretinide (4HPR) suppress HL-60 leukemia cell growth and cause partial cell arrest in the G 1 -to-S phase. Moreover, 4HPR but not RA induces apoptosis in HL-60 cells. To investigate further the observed biological effects, cyclin D1 and