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Induction of apoptosis byMyagropsis myagroidesextracts is associated with a caspase dependent pathway and reactive oxygen species generation in human cancer cells

✍ Scribed by Byoung Ok Cho, Hyung Won Ryu, Yangkang So, Chang Hyun Jin, Myung-Woo Byun, Dong Hyun Ahn, Il Yun Jeong

Book ID: 118791433
Publisher: The Korean Society of Food Science and Technology
Year: 2012
Tongue: English
Weight: 539 KB
Volume: 21
Category: Article
ISSN: 1226-7708
DOI: 10.1007/s10068-012-0180-4

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## Abstract Exogenous β~2~‐microglobulin (β~2~m) induces significant apoptosis in the CCRF‐HSB‐2 human lymphoblastic leukemia cell line as detected by DNA fragmentation, DAPI staining and annexin V binding assay. β~2~m treatment induced the release of cytochrome c and apoptosis‐inducing factor (AIF