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Induction of apoptosis by Trichostatin A in human breast cancer cell lines: involvement of 15-Lox-1

✍ Scribed by Tavakoli-Yaraki, Masoumeh; Karami-Tehrani, Fatemeh; Salimi, Vahid; Sirati-Sabet, Majid

Book ID
118302895
Publisher
S. Karger AG
Year
2012
Tongue
English
Weight
268 KB
Volume
34
Category
Article
ISSN
1010-4283

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The purpose of this study was to document induction of apoptosis by vitamin E succinate (VES; RRR-Ξ±-tocopheryl succinate) in human breast cancer cells in culture and to characterize potential c-jun involvement. VES at 18.8 Β΅M (10 Β΅g/mL) induced DNA synthesis arrest, reduced total cell numbers, and i