Induction of apoptosis by the novel retinoid AHPN in human T-cell lymphoma cells involves caspase-dependent and independent pathways
โ Scribed by Adachi, Hiroshi; Adams, Anthony; Hughes, Francis M; Zhang, Jiandi; Cidlowski, John A; Jetten, Anton M
- Book ID
- 110015848
- Publisher
- Nature Publishing Group
- Year
- 1998
- Tongue
- English
- Weight
- 339 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1350-9047
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Retinoids are promising agents for the prevention and treatment of several human malignancies including lung cancer. However, many lung cancer cell lines are resistant to the growth inhibitory effects of all-trans-retinoic acid (ATRA). Recently, we found that a new synthetic retinoid, 6-[3-(1-adaman
## Abstract A p53 Cโterminal peptide (aa 361โ382, p53p), fused at its Cโterminus to the minimal carrier peptide of __antennapedia__ (17 aa, Ant; p53pโAnt), induced rapid apoptosis in human cancer cells, __via__ activation of the Fas pathway. We examined p53pโAnt mechanism of action, toxicity in var
## Abstract Exogenous ฮฒ~2~โmicroglobulin (ฮฒ~2~m) induces significant apoptosis in the CCRFโHSBโ2 human lymphoblastic leukemia cell line as detected by DNA fragmentation, DAPI staining and annexin V binding assay. ฮฒ~2~m treatment induced the release of cytochrome c and apoptosisโinducing factor (AIF