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Induction of apoptosis by an inhibitor of EGFR in neuroblastoma cells

✍ Scribed by Shinichi Tamura; Hajime Hosoi; Yasumichi Kuwahara; Ken Kikuchi; Osamu Otabe; Moriatsu Izumi; Kunihiko Tsuchiya; Tomoko Iehara; Takahiro Gotoh; Tohru Sugimoto


Book ID
116294897
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
597 KB
Volume
358
Category
Article
ISSN
0006-291X

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The survival, proliferation and differentiation of neuroblastoma (NB) cells are largely dependent on adhesion to extracellular matrix (ECM) proteins. Integrin occupancy seems to play a primary role. To elucidate the role of integrin heterodimers during neuronal cell death, we have analysed the chang