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Induction of apoptosis and reactive oxygen species production by N-nitrosopiperidine and N-nitrosodibutylamine in human leukemia cells

✍ Scribed by Almudena García; Paloma Morales; Nuria Arranz; Eugenia Delgado; Ana I. Haza

Book ID
119379334
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
79 KB
Volume
172
Category
Article
ISSN
0378-4274

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## Abstract __N__‐nitrosopiperidine (NPIP) and __N__‐nitrosodibutylamine (NDBA) belong to a group of __N__‐nitrosamines that are widely distributed in foodstuffs and the occupational environment. In the present study, the human promyelocytic leukemia cell line HL‐60, was used to characterize the ap

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## Abstract The aim of this work was to determine the effect of vitamin C, diallyl disulfide (DADS) and dipropyl disulfide (DPDS) towards __N__‐nitrosopiperidine (NPIP) and __N__‐nitrosodibutylamine (NDBA)‐induced apoptosis in human leukemia (HL‐60) and hepatoma (HepG2) cell lines using the termina