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Induction of anti-tumor immunity in vivo using cytokines and an agonistic antibody against 4-1BB

โœ Scribed by L. Borges; R.E. Miller; J. Jones; D.H. Lynch


Book ID
117658441
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
354 KB
Volume
37
Category
Article
ISSN
0959-8049

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โœ Masaki Kimura; Yu Yoshida; Mitsuro Narita; Keizo Takenaga; Toshinao Takenouchi; ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 330 KB ๐Ÿ‘ 2 views

We have examined the anti-tumor effect in nude mice caused by human pancreatic cancer cells (AsPC-1) modified to secrete IL-2 or IL-4. Loss of tumorigenicity of cytokineproducing, but not wild-type, cells was observed despite their unaltered in vitro proliferation rates; and these anti-tumor effects